IBS is a disorder of heterogeneous pathophysiology for which there are no good diagnostic tests nor effective treatments (online study on unmet needs conducted by IFFGD and UNC). Existing tests are performed to exclude diseases such as IBD, colorectal cancer, diseases associated with malabsorption, systemic hormonal disturbances, and enteric infections.
Routine serologic screening for celiac sprue in patients with IBS-D or IBS-M may be useful.
Lactose intolerance can cause IBS-D, intolerances to other food groups such as
Image via Wikipediafructose could be also implicated. Problems with serotonin signaling, or the transmission of messages between the nerves, can lead to IBS-C
- New Guidelines Issued for Management of IBS (download pdf)
Most IBS treatments relieve symptoms rather than resolve the condition itself.
The new guidelines encompass existing evidence on conventional treatments for IBS as well as new therapies (probiotics, for example) and alternative therapies (acupuncture and more).
Fiber products -- including psyllium, anti-spasmodic medications and peppermint oil -- may be effective in some people. "The evidence is poor, but some patients say they feel better,"
More data is needed on probiotics, live microorganisms (usually bacteria) similar to the "good" organisms found normally in the gut. The dichotomous data suggest that all probiotic
therapies have a trend for being efficacious in IBS, whereas the
continuous data indicate that Lactobacilli have no impact on
symptoms; probiotic combinations improve symptoms; and
there is a trend for Bi fidobacteria to improve IBS symptoms.Researchers and practitioners still need to figure out the species of bacteria used, how many species, and dosages.
Non-absorbable antibiotics -- those targeted to the gut only, such as rifaximin (Xifaxan) -- also seem to help some people, especially those who have "diarrhea-predominant IBS."
Selective C-2 chloride channel activators, notably lubiprostone (Amitiza), are effective for "constipation-predominant IBS."
5HT 3 antagonists such as alosetron (Lotronex) relieve symptoms of diarrhea but can cause constipation and colon ischemia, a restriction of blood flow.
5HT 4 agonists, though effective against constipation, are not available in North America because of a heightened risk of cardiovascular problems.
There is yet to be conclusive evidence on Chinese herbal mixtures, and the mixtures run the risk of causing liver failure and other problems. Differences in the content of compounds and the purity of ingredients complicate evaluation of benefits.
Similarly, the evidence on acupuncture remains inconclusive.
There is no evidence at this point that testing for food allergies or following diets that exclude certain foods alleviates IBS symptoms.
Routine diagnostic testing for IBS is not recommended, although some testing should be performed in certain subgroups of patients.
More about IBS at the U.S. National Institute of Diabetes and Digestive and Kidney Diseases site.
- IBS medications: http://www.ibsgroup.org/medications. compiled by IBS Self Help and Support Group
To ease IBS with diarrhea, avoid fried foods, too much fiber, especially insoluble such as apple skins, chocolate, alcohol, caffeine, carbonated drinks, the artificial sweetener sorbitol (found in sugarless gum and mints), and fructose (the simple sugar found in honey and many fruits). These can worsen diarrhea symptoms. Drink six to eight glasses of plain water a day - not with meals, but an hour before or an hour after meals. Avoid drinking hot teas.
Not Censored IBS Diet Links:
- IBS Resources from About.com
- IBS diet and recipes from helpforibs
- Diet for IBS by Diettrific
- IBS Diet suggestions
- IBS Diet Resources
- IBS articles on pubmed
- IBS Video from NHS
- Coping with IBS by WebMD
- American College of Gastroenterology
- International Foundation for Functional Gastrointestinal Disorders
- Symptoms f IBS by symptomsofibs.org
- Irritable Bowel Syndrome Association folded into the INS support group in 2009
- IBS Resource on Squidoo
- Irritating IBS on Diabetes Self-Management Blog
- Managing IBS by American Family Physician
- is IBS linked to foods?
- The Irritable Bowel Syndrome Self Help and Support Group is an award-winning patient advocate group in support of self-management for IBS sufferers. Learn how sufferers are living day-to-day with IBS. Read success stories about strategies that sufferers use to cope with IBS. At the Irritable Bowel Syndrome Self Help and Support Group: You are not alone
- IBS group on twitter
- Digestive Health SmartBrief News and Briefs on Digestive Health and Foodborne illnesses
- Body Odor Support Group: An online support group for people with all types of body odor disorders, including TMAU, IBS and other medically not recognized or characterized conditions.
- Only 8% of IBS patients are satisfied with existing solutions, many agree to assume risks to be symptom free
- Unmet needs of IBS patients (view survey report (pdf))
- Children whose celiac disease is detected early do better over time
Image via Wikipedia
- From 3% to 10% of IBS also have celiac disease
- Too much fruit is not good for you
- Daily recommended fiber intake
- 45% of IBS patients have lactose intolerance
- 65% of children with IBS have SIBO
Diarrhea-prominent IBS: wheat, beef, pork, and soybean. Constipation-prominent IBS: wheat, lamb, beef, and pork. Alternating IBS: wheat, beef, and pork, 2005 study
- IBS is on the rise Dr. Hildreth
- IBS is on the rise, Times of India
- Fructose and IBS by Dr. Mirkin
- Fructose, Sucrose and IBS, by D. Brown
- Food additives, packaging chemicals and IBS
- Dr. Groves on IBS and other unrecognized health conditions
International Foundation for Functional Gastrointestinal Disorders (IFFGD) sites:
|Acid Reflux Disease (GERD)||aboutGERD.org|
|Irritable Bowel Syndrome (IBS)||aboutIBS.org |
|Incontinence or Urgency||aboutIncontinence.org|
|Digestive Disorders in Kids |
|Digestive Health Research||giResearch.org|
- Y! answers
- IBS Blood test by Prometheus
- Only 8% of IBS patients are satisfied with existing solutions, many agree to assume risks to be symptom free, results from a survey based on 1,966 qualifying responses (see pdf-formatted report)
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