Friday, June 26, 2009

To Test or Not to Test: Myalgic Encephalomyelitis/Encephalopathy/Chronic Fatique Syndrome

by Aurametrix

A number of medical conditions is associated with altered body odor. Myalgic Encephalomyelitis/Encephalopathy/Chronic Fatique Syndrome may be one of them. Hydrogen Sulfide Urine Test was developed and is available for at-home use. Most people, however, prefer to use their nose instead, pointing that I also note that Prof. Kenny de Meirleir's work on testing was not published in a Peer Reviewed Journal.

And what abut Candida overgrowth that usually is not associated with excess hydrogen sulfide?

Biomed diagnostics offers inexpensive tests for Candida species.
Their InTrayTM ColorexTM Screen also detects E.coli, Proteus mirabilis, Enterococcus sp., Klebsiella pneumnaiae, Staphylococcus aureus bacteria
and Dermatophytes fungi.

Many tests are available for urinary tract infections and various metabolites in urine.

Here is SlideShare Presentation by Kenny De Meirleir on ME/CFS, hydrogen sulfide and aberrant prion disease:
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Sunday, June 14, 2009

Fun Ways to Learn about Food & Foodborne diseases

Mirrored from Aurametrix

Let me introduce E.coli (on the left) and Salmonella (on the right), pictured by GaintMicrobes company.

You can get acquainted with these guys even closer if you (or the food manufacturer) do not follow the safety rules.

You can learn more about it and from these fun games, some of which were presented at the 5th annual Games for Change Festival. and mentioned in the Mission to Learn blog.

Browser-based, Free Learning Games

Safe Food Park

Hey, hop on! The Food Safety Mobile is about to take a ride through SAFE FOOD PARK. Learn about invisible enemies that are always ready so strike If you are not careful when handling and preparing food it could make you and your family sick

Food Detectives Fight BAC

“The Food Detectives Fight BAC!® game gives kids a fun way to learn about foodborne illness. More and more, foodborne illness is making news headlines. According to the Center for Disease Control and Prevention (CDC), foodborne illnesses in the United States affect millions of people and cause thousands of deaths every year. The CDC says 300,000 people are hospitalized every year.” From New Mexico State University.

The Incredible Adventures of the Amazing Food Detectives

“There has been a mysterious outbreak of unhealthy habits hitting too many boys and girls. If we don’t solve these cases, and fast, kids might not make the right food and exercise choices as they grow, and that could be trouble! All junior food detectives will get secret training on how to eat right and exercise. You can investigate fun games like Whack A Snack, Soccer, and Zap the TV. Plus you can print out classified clues on ways to be healthy, then share them with your parents, teachers, and pals.” From Kaiser Permanente. Teacher resources available.

Desktop/Free Learning Games

All of the following are free, though in most instances donations are encouraged.

Food Force
“As team rookie you have six missions to complete. Each mission represents a part of the process of delivering food aid to an area in crisis. The final mission shows you how food aid can help people rebuild their lives in the years following a disaster.” United Nations World Food Programme. Multiple languages. Teacher resources available.

“FATWORLD is a video game about the politics of nutrition. It explores the relationships between obesity, nutrition, and socioeconomics in the contemporary U.S. The game’s goal is not to tell people what to eat or how to exercise, but to demonstrate the complex, interwoven relationships between nutrition and factors like budgets, the physical world, subsidies, and regulations. Existing approaches to nutrition advocacy fail to communicate the aggregate effect of everyday health practices. It’s one thing to explain that daily exercise and nutrition are important, but people, young and old, have a very hard time wrapping their heads around outcomes five, 10, 50 years away.”

Immune Attack
This game teaches immunology in a fun and engaging way that is different from the traditional classroom setting. For example, you can train monocytes to transmigrate out of the blood vessel network and pass into the connective tissue, train the macrophage to follow the chemical trail of C3as leading to the site of infection (the Pseudomonas bacteria), activate receptors to recognize enemies and watch the macrophage eat them.

Saturday, June 13, 2009


Mirrored from Aurametrix

According to the National Scoliosis Foundation, scoliosis, a condition that causes an abnormal curvature of the spine, affects approximately 3% of the U.S. population, which roughly equals 6 million people.

Scoliosis impacts infants, adolescents, and adults of all races and socio-economic status. The primary age of onset for scoliosis is 10-15 years old, occurring equally among both genders. However, females are eight times more likely to progress to a curve magnitude that requires treatment.

Scoliosis can impact the quality of life with limited activity, pain, reduced respiratory function, or diminished self-esteem.

The vast majority of people with this condition (if they are still growing and the severity of spinal curvature is less than 25 degrees) are not expected to require treatment. Observation is also the preferred option for moderate curvature (less than 40 to 45 degrees) in people who have finished growing. In some cases, the observed curve is temporary, resulting from inflammation, muscle spasms or having one leg that is longer than the other. Patients who are diagnosed with scoliosis, however, should be examined regularly, about every four to six months, to make sure that the curvature hasn’t worsened.

Exercise can reduce the symptoms. Significant curve reduction due to specialized strength training was reported by a spine clinic in San Diego. A study from the University of Athens on aerobic training for patients with idiopathic scoliosis showed that the ability to perform perform aerobic work increased 48.1% in the training group, while it decreased 9.2% in the control group.

New treatments are also emerging. The SpineCorporation LTD, developer of the SpineCor brace for adolescent Scoliosis, recently released the first Dynamic Flexible Adult Scoliosis Brace (shown on the left).

Scoliosis is closely linked to low bone densities, yet we know that bone densities are influenced by a wide variety of overlapping factors that includes genes, estrogen levels, nutrition, exercise levels and drugs. We still do not know who will get it, why they get it, which will progress, or how far they will progress. In animal studies, scoliosis is known to be caused by a wide variety of conditions including lack of physical activity, pesticide exposure and nutritional deficiencies. Some of these are the same conditions, especially the lack of exercise and nutritional deficiencies, that are known to lower bone densities in humans.

Scoliosis has been induced in a variety of animals through the creation of nutritional deficits and imbalances.

Scoliosis is a multifactorial disorder, which requires multidisciplinary research and treatment.

Aurametrix is an early phase company working on Health3.0 & Health 4.0 technologies
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Monday, June 8, 2009

Microbes we live with

Mirrored from Aurametrix

Just a few hours after birth, every human being is colonized by more microbes than there are cells in the body. We are home to thousands of species of bacteria, protists, algae, fungi, molds and viruses.

Some of these microbes help us to develop blood vessels in the gut, digest our food and train our immune system. Others make us sick, contributing to skin diseases, body odor, malabsorption, gastrointestinal problems, ear infections and more. Some of such bacteria can be even found in bottled water.

The composition and distribution of microbial populations depend on the age, diet, fitness, genetics, hygiene, and overall state of health of their hosts.

Dr. Bonnie Bassler, of Princeton University, gives an estimate of how many bacteria live on us in her Ted talk, at the 2009 TED Conference. Number of human cells in the average adult = 1 trillion. Number of bacteria cells in association with the average adult = 10 trillion. Even more intriguing, is the number of genes that humans have is about 30,000. How many different bacteria genes are associated with us? 300,000! So, are we human or are we bacteria?

Aurametrix has one the most complete databases of species found on human body and in human food.

Check these sites for more info on our little companions:


finished/draft Total
Bacteria 781/503 1284
Archaea 56/3 59
Eukarya 19/30 49
Plasmids 974/0 974
Viruses 2524/0 2524
All Genomes 4354/536 4890
Genome by Metadata
IMG Statistics
Project Map
Content History

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Wednesday, June 3, 2009

How many types of headache are known?

(2/365) Ow headache...Image by Sarah G... via Flickr
There are more than 300 types of headaches, but only about 10% of headaches have a known cause. The others are called primary headaches.
Check the web-based 2nd Edition of The International Classification of Headache Disorders (ICHD-2) for details on their diagnostic criteria:
Here is a partial list from Aurametrix database:


Primary headaches

R51 Headache as Facial Pain NOS (excluding atypical pain, neuralgia, migraine)
G43 Migraine

G43.0 Migraine without aura [common migraine]
G43.1 Migraine with aura [classical migraine]
G43.2 Status migrainosus
G43.3 Complicated migraine
G43.8 Other migraine (Ophthalmoplegic, Retinal, etc)
G43.9 Migraine, unspecified
G44.0 Cluster headache and other trigeminal autonomic cephalalgias (TAC)

Chronic Cluster headache syndrome

Episodic Cluster Headache

Chronic paroxysmal hemicrania

G44.1 Vascular headache, not elsewhere classified Vascular headache NOS
G44.2 Tension-type headache (TTH) Stress Headache

Chronic tension-type headache

Episodic tension headache

Tension headache NOS

G44.3 Chronic post-traumatic headache

G44.4 Drug-induced headache, not elsewhere classified

G44.8 Other specified headache syndromes

G44.803 Primary cough headache

G44.804 Primary exertional headache

Hypnic headache

Primary thunderclap headache

Hemicrania continua

New daily persistent headache (NDPH)

G44.805 Primary headache asspciated with sexual activity Coital cephalalgia

Preorgazmic headache

Orgazmic headache

G44.882 Cardiac Cephalalgia

Headache attributed to disorder of homoeostasis not sufficiently validated

G44.882 headache attributed to hypoxia and/or hypercapnia
G44.882 Dialysis headache

G44.813 Headache attributed to arterial hypertension

G44.882 Headache attributed to hyperthyroidism

G44.882 Headache attributed to fasting

Secondary headaches

Space Headache

S00-S09 Head injury Headache attributed to head and/or neck trauma
I61 Intracerebral hemorrhage Headache attributed to cranial or cervical vascular disorder Excludes: sequelae of intracerebral haemorrhage ( I69.1 )
I61.0 Intracerebral haemorrhage in hemisphere, subcortical Headache attributed to cranial or cervical vascular disorder

Deep intracerebral haemorrhage

I61.1 Intracerebral haemorrhage in hemisphere, cortical

Cerebral lobe haemorrhage

Superficial intracerebral haemorrhage

I61.2 Intracerebral haemorrhage in hemisphere, unspecified
I61.3 Intracerebral haemorrhage in brain stem

I61.4 Intracerebral haemorrhage in cerebellum

I61.5 Intracerebral haemorrhage, intraventricular

I61.6 Intracerebral haemorrhage, multiple localized

I61.8 Other intracerebral haemorrhage

I61.9 Intracerebral haemorrhage, unspecified

I60 Subarachnoid hemorrhage

I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
I60.1 Subarachnoid haemorrhage from middle cerebral artery
I60.2 Subarachnoid haemorrhage from anterior communicating artery
I60.3 Subarachnoid haemorrhage from posterior communicating artery
I60.4 Subarachnoid haemorrhage from basilar artery

I60.5 Subarachnoid haemorrhage from vertebral artery

I60.6 Subarachnoid haemorrhage from other intracranial arteries

Multiple involvement of intracranial arteries

I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified

Ruptured (congenital) berry aneurysm NOS

Subarachnoid haemorrhage from cerebtal artery NOS

Subarachnoid haemorrhage from communicating artery NOS
I60.8 Other subarachnoid haemorrhage

Meningeal haemorrhage

Rupture of cerebral arteriovenous malformation

I60.9 Subarachnoid haemorrhage, unspecified

Ruptured (congenital) cerebral aneurysm NOS

M31.5 Giant cell arteritis

G93.2 Idiopathic intracranial hypertension Headache attributed to non-vascular intracranial disorder
G97.1 Post dural puncture headaches Headache attributed to non-vascular intracranial disorder
G40-G47 Ictal headache Associated with seizure activity

G44.4 or G44.83 Medication overuse headaches Headache attributed to a substance or its withdrawal
G44.4,44.83,F10,F13,F19,P96 Medication or drug withdrawal headaches MeSH

G00 Meningitis Headache attributed to infection

G50.1 Atypical facial pain attributed to disorder of cranium, neck, eyes, ears, nose, sinuses, teeth, mouth or other facial or cranial structures
J01 Sinusitis

R51 Headache attributed to psychiatric disorder

G44.847, G.44.848 or G44.85 Cranial neuralgias, central and primary facial pain and other headaches

Trigeminal neuralgia

Glossopharyngeal neuralgia

Nervus intermedius neuralgia

Superior laryngeal neuralgia

The most common type of headache is a tension headache. Some people experience headaches when they are hungry or dehydrated. Other common reasons include performing an activity that causes you to hold your head in one position for a long time (like using a computer, microscope, or typewriter), sleeping in a cold room or an abnormal position, overexerting yourself, clenching your jaw or grinding your teeth.

Major migraine triggers for men

  • Changing weather: rising humidity, heat
  • Lack of sleep or oversleeping
  • Fatigue
  • Emotional Stress
  • Sensory triggers: bright or flickering lights, loud noises, strong smells
  • Dietary triggers:

    • missing a meal
    • alcohol, especially red wine
    • chocolate
    • nitrates in cured meats and fish
    • aged cheese
    • an increase or decrease in caffeine
    • MSG (often present in Asian and prepared foods)

    18 most common sources of headache:
    1.  Stress
    2.  Not enough sleep
    3.  Certain foods and food additives, such as chocolate, cheese, caffeine and monosodium glutamate (MSG).
    4.  Grinding your teeth
    5.  Depression and anxiety
    6.  Skipping meals
    7.  Poor posture
    8.  Lack of exercise
    9.  Holding your head or neck in an awkward position for a long time
    10. Hormonal changes related to menstruation (PMS), menopause, pregnancy or hormone use
    11. Medications, including those for depression and high blood pressure, or overusing headache medication
    12. Overexerting yourself
    13. Sleeping in an awkward position
    14. Eye strain
    15. Fatigue
    16. Smoking
    17. Alcohol
    18. Sinus infections, colds or flu

    Aurametrix is a company developing Health 4.0 technologies
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    Tuesday, June 2, 2009

    Can dogs detect cancer? Invitation to event

    Can Dogs Detect Cancer?

    A movie, demo, and discussion about dog scent detection and ovarian cancer

    Wednesday June 10th 6-7 pmdogs sniffing cancer
    LGBT Center, 1800 Market St @ Octavia
    San Francisco, CA
    Cost: FREE
    Free childcare available during the event
    by RSVP to (415) 342-0886

    Come hear about groundbreaking, federally funded, ovarian cancer research being conducted in the bay area and learn more about the symptoms and risks of ovarian cancer.

    A documentary will be shown and there will be Q&A with Pine Street Foundation’s Principal Investigator, Michael McCulloch, LAc, MPH, PhD.
    Watch a live demo and meet “Tessy”, the dog featured in this month’s Oprah Magazine article, “Sniffing Out Cancer”.

    Representatives from the San Francisco chapter of The National Ovarian Cancer Coalition will be available for information and questions.

    Women who are interested in donating a breath sample at the event may call (415) 342-0886 by Friday June 5th. Breath samples are sought from non-smoking women, 21+, who have been recently diagnosed with ovarian cancer, polycystic ovarian syndrome (PCOS), or endometriosis.


    Frequently Asked Questions
    Can dogs really detect cancer? How did you collect breath samples? Click here for answers to these questions and more.

    Canine Scent Detection of Ovarian Cancer
    This study is currently in progress. Click here for the latest on this study as well as how you can participate.

    Canine Scent Detection of Lung and Breast Cancer
    This ground-breaking study was published in 2006. Click here for more information about this research as well as the full paper.

    Aurametrix is an early phase company working on Health 4.0 technologies
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    Monday, June 1, 2009

    Bioactive Components of Food

    Bioactive Components of Food
    Food Component
    If too little
    Upper and lower limits
    If too much

    Dietary Protein
         ~105 types
    • allergies
    7%-40% of total calories7%-40% of total calories (0.8 grams per kilogram of body weight)
    • stomach upsets
    • FDA daily reference values, 4-2008

    • poor recovery from physical stress

    • dehydration
    • FDA recommended healthy diet

    • difficulty sleeping

    • bad breath/body odor
    • Daily Values for Children

    • fatty liver

    • gout
    • Protein supplements for weight training

    EF-hand protein

    • calcium loss
    • Best proteins for muscle growth


    • damage to the liver and kidneys.
    • Promax Pros and Cons


    • reduced endurance
    • Rice Protein Guide

    Plant enzymes

    • Spirulina Side Effects

    Dietary Carbohydrate
         ~102 types
    • nausea
    40%-60% of total calories
    • fatigue

    o Monosaccharides (Fructose, Glucose, Galactose)
    • fatigue, dizziness

    increased hyperactivity
    • Low-carb diets may hamper memory

    o Disaccharides (Lactose, Sucrose, Maltose)
    • feeling frustration

    tooth decay
    • Clinical Nutrition Journal article on too much carbs in diet

    o Oligosaccharides (Raffinose, Stachyose)
    • light-headedness

    heart disease
    • PloS Genetics article on why too much sugar decreases lifespan

    o Polysaccharides (starch, dietary fiber, mucilage)
    • tiredness

    type 2 diabetes
    • Dr. McDougall’s Money-Saving Medical Advice

    o Nucleotides
    • gout

    yeast infections
    • Fat No More by Sandra Prior

    • bad breath, odor of alcohol

    candida overgrowth

    • headache

    digestive problems

    • kidney stones


    • ketosis (muscle wasting), blood acidosis


    kidney disease

    liver disease



    Dietary Lipid (Fat)
    ~103 types, examples of classes found in food:
    • Hair falling out
    15-35 of total calories

    • Coronary Heart Disease
    • MedlinePlus Medical Encyclopedia: Fat

    saturated fatty acids
    • Hair loosing luster and sheen

    • Diabetes
    • Diet Bites

    monosaturated fatty acids
    • Nails becoming brittle, hard and curly

    • NY Times article

    polyunsaturated fatty acids
    • Vital organs lacking cushion

    • Gallstones

    • Difficulties to maintain body temperature



    • Thirst
    2 qts-10 liters (2-3 liters), ~volume of excreted fluid
    • blurred vision
    • Too Much Water Can Kill

    • Loss of Appetite

    • muscle cramps
    • Water intoxication

    • Dry Skin

    • confusion
    • Dehydration

    • Skin Flushing

    • seizures

    • Dark Colored Urine

    • coma

    • Dry Mouth

    • Fatique or Weakness

    • Chills

    • Head Rushes

    Dietary Minerals
    • elevated blood pressure
    • cardiac arrhythmias,
    • muscular weakness
    • myalgia
    • muscle cramps
    • constipation
    • flaccid paralysis
    • hyporeflexia
    • tetany

    3,500 mg
    • malaise,
    • palpitations
    • muscle weakness
    • cardiac arrhythmia
    • sudden death.

    • Low Potassium Diet Recipes

    Sweating, tremor, anxiety, tachycardia, hunger, dizziness, reduced mental acuity, visual abnormalities, convulsions and loss of consciousness
    3,400 mg
    Kussmaul's breathing, weakness, intense thirst.

    Increased risk of heart attack, Swelling of the brain

    lethargy, weakness, irritability, edema, seizures, coma
    • Dietary minerals

    Off spots, rashes, tingling and parasthesia, spasms, hyperactive tendon reflexes, cardiac arrhythmias
    1 gram
    (1.2g if 50+)

    fatigue, depression, confusion, anorexia, nausea, vomiting, constipation, pancreatitis or increased urination
    • Medical Encyclopedia: Poisoning

    Muscle dysfunction and weakness, irritability, gross confusion, delirium, coma, worsening of infections, rhabdomyolysis, hemolytic anemia.
    700 mg-1,000 mg

    ectopic calcification, secondary hyperparathyroidism, and renal osteodystrophy

    Hypertension, cardiovascular disease, Vitamin K deficiency, depressed immunity, depression, diabetes, erectile dysfunction, increased levels of stress, insomnia, fasciculation, migraine, cancer, ADHD, asthma, Restless Leg Syndrome, and allergies
    Women: 310-320 mg
    Men: 400-420 mg

    Weakness, nausea and vomiting, diarrhea, Impaired breathing, Hypotension, Hypocalcemia, Arrhythmia and Asystole
    Magnesium - the stress buster

    hair loss, skin lesions, diarrhea, wasting of body tissues. Damage of eyesight, taste, sense of smell and memory, acne. Leukonychia (white spots on the fingernails), dysmenorrhea
    15 mg (30mg)
    "zinc chills", Vomiting, Diarrhea, Drowsiness

    fatigue, pallor, irritability, weakness, pica, brittle or grooved nails, painful atrophy of the mucous membrane covering the tongue, the pharynx and the oesophagus, impaired immune function
    18 mg
    Fatigue, Weakness, Weight loss, Joint pain, Abdominal pain; Arthritis, Symptoms of Gonadal failure, Dyspnea or shortness of breath

    iron overload

    Ataxia, fainting, hearing loss, weak tendons and ligaments; skeletal deformations, delayed wound healing
    2.3 mg (tolerable: 11 mg)

    tremors, odd movements, a mask–like face, and body stiffness; hallucinations, confusion, and memory loss.
    How much is too much?

    spasticity, severe gait abnormalities including ataxia, and a neuropathy.
    900 µg
    mild headaches, lightheadedness, convulsions, palsy, and insensibility

    Fatigue, Thyroid disease, Breast, ovarian, and skin cysts, poor digestion, Dementia, Glaucoma, Parkinson's; Deafness in children of iodine defficient mothers
    150 µg
    burning in the mouth, throat and stomach and/or abdominal pain, nausea, vomiting, dirarrhea, weak pulse, and coma

    extreme fatigue, hyperthyroidism, mental slowing, goitre, cretinism and recurrent miscarriage
    55-70 µg
    hair loss , tenderness and swelling on the fingertip, garlic breath/body odor

    combined enzyme deficiency, severe neurological abnormalities, dislocated ocular lenses, mental retardation, increased urinary excretion of sulfite, thiosulfate, S-sulfocysteine, taurine, hypoxanthine and xanthine, and reduced serum and urine levels of sulfate and urate
    45 µg
    Cough, phlegm, shortness of breath, wheeze. Rhinitis, eye irritation., acute anemia

    loss of appetite, emaciation, weakness, anemia
    5-40 µg
    Cough. Laboured breathing. Shortness of breath.Dry skin, Redness, Abdominal pain, Vomiting


    up to 1 mg
    decreased body weight, heart and liver damage, and skin irritation


    Carotene, alpha

    lung cancer
    in smokers

    • Vitamin overdose

    Carotene, beta

    • Multiple vitamin overdose



    L-Carnitine Side Effects

    Cryptoxanthin, beta

    Folate, DFE, Folic acid , Vitamin B9, folacin

    Lutein, zeaxanthin




    (20 mg tolerable)

    Pantothenic acid


    Riboflavin (B2)


    Thiamin (B1)

    Women: 1.1 mg
    Men: 1.2 mg (<1.5>

    Vitamin A

    700-900 mcg

    Vitamin B-12

    Vitamin B-6

    Vitamin Bt (L-carnitine)

    Vitamin C, ascorbic acid

    Vitamin E (alpha-tocopherol)


    Vitamin K (phylloquinone)


    • Amino Acid Supplements


    • Maximuscle Promax


    Aspartic acid


    Glutamic acid















    10 genera, ~103 strains

    Webmd on Probiotics

    Bacteroides sp.

    Wikipedia on Probiotics

    Bifidobacterium bifidum

    Bifidobacterium infantis 35624 (Align_, could help IBS

    Bifidobacterium lactis Bb-12 (available in Yo-Plus yogurt, LiveActive cheese).

    Chronic fatigue

    Bifidobacterium lactis HN019. good for older people

    Lactobacillus sp.

    Lactobacillus acidophilus CL1285 plus Lactobicillus casei Lbc80r (available as BioK + CL1285 fermented milk, BioK + CL1285 soy milk, and capsules).

    Lactobacillus casei DN-114 001 (in DanActive products).

    Lactobacillus casei DN-114 001 (in DanActive products).

    Lactobacillus plantarum 299V (NextFoods, Ferring)

    Lactobacillus reuteri ATCC55730 (available in BioGaia Gut Health products).

    Lactobacillus rhamnosus GG (LGG) (in Danimals drinkable yogurt and Culturelle capsules).

    Lactobacillus rhamnosus GG (LGG) (in Danimals drinkable yogurt and Culturelle capsules).

    S. cerevisiae (S. boulardii) (Florastor powder and Lalflor capsules).

    Hydrolyzable tannins (gallic acid esters of glucose and other sugars)

    • Herbal Teas


    Condensed tannins

    Other Bioactive Food and Drink Compounds
    Allyl-S compound





    Dietary Alcohol

    Dietary Ash

    Food Ash Charts

    Hydroxybenzoic Acid









    Mirrored from Aurametrix

    Aurametrix works on automatic solutions to monitor and analyze food intake, along with many other aspects of daily living.  Better solutions for a healthier world.
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