Thursday, May 7, 2009

IBS Resources

Mirrored from Aurametrix

IBS is a disorder of heterogeneous pathophysiology for which there are no good diagnostic tests nor effective treatments (online study on unmet needs conducted by IFFGD and UNC). Existing tests are performed to exclude diseases such as IBD, colorectal cancer, diseases associated with malabsorption, systemic hormonal disturbances, and enteric infections.
Routine serologic screening for celiac sprue in patients with IBS-D or IBS-M may be useful.
Lactose intolerance can cause IBS-D, intolerances to other food groups such as

Percentage of population with IBS reported in ...Image via Wikipedia

fructose could be also implicated. Problems with serotonin signaling, or the transmission of messages between the nerves, can lead to IBS-C

The guidelines, issued by the American College of Gastroenterology were published in the January2009 issue of The American Journal of Gastroenterology.

Most IBS treatments relieve symptoms rather than resolve the condition itself.

The new guidelines encompass existing evidence on conventional treatments for IBS as well as new therapies (probiotics, for example) and alternative therapies (acupuncture and more).

Fiber products -- including psyllium, anti-spasmodic medications and peppermint oil -- may be effective in some people. "The evidence is poor, but some patients say they feel better,"

More data is needed on probiotics, live microorganisms (usually bacteria) similar to the "good" organisms found normally in the gut. The dichotomous data suggest that all probiotic
therapies have a trend for being efficacious in IBS, whereas the
continuous data indicate that Lactobacilli have no impact on
symptoms; probiotic combinations improve symptoms; and
there is a trend for Bi fidobacteria to improve IBS symptoms.Researchers and practitioners still need to figure out the species of bacteria used, how many species, and dosages.

Non-absorbable antibiotics -- those targeted to the gut only, such as rifaximin (Xifaxan) -- also seem to help some people, especially those who have "diarrhea-predominant IBS."

Selective C-2 chloride channel activators, notably lubiprostone (Amitiza), are effective for "constipation-predominant IBS."
5HT 3 antagonists such as alosetron (Lotronex) relieve symptoms of diarrhea but can cause constipation and colon ischemia, a restriction of blood flow.
5HT 4 agonists, though effective against constipation, are not available in North America because of a heightened risk of cardiovascular problems.

There is yet to be conclusive evidence on Chinese herbal mixtures, and the mixtures run the risk of causing liver failure and other problems. Differences in the content of compounds and the purity of ingredients complicate evaluation of benefits.

Similarly, the evidence on acupuncture remains inconclusive.

There is no evidence at this point that testing for food allergies or following diets that exclude certain foods alleviates IBS symptoms.

Routine diagnostic testing for IBS is not recommended, although some testing should be performed in certain subgroups of patients.

More about IBS at the U.S. National Institute of Diabetes and Digestive and Kidney Diseases site.


To ease IBS with diarrhea, avoid fried foods, too much fiber, especially insoluble such as apple skins, chocolate, alcohol, caffeine, carbonated drinks, the artificial sweetener sorbitol (found in sugarless gum and mints), and fructose (the simple sugar found in honey and many fruits). These can worsen diarrhea symptoms. Drink six to eight glasses of plain water a day - not with meals, but an hour before or an hour after meals. Avoid drinking hot teas.

To ease IBS with constipation, drink water and exclude beverages as suggested above. Eat small frequent meals and be careful with fiber. Soluble is better at reducing severety of symptoms, as was shown in this 2005-2007 clinical trial, but all types of fiber could potentially worsen the syndrome. You may also want to exclude broccoli and other dark green vegetables from your diet. Keep an IBS symptom journal, it would help you and your doctor to find what foods and situations trigger your IBS symptoms.

Not Censored IBS Diet Links:

More Links:


International Foundation for Functional Gastrointestinal Disorders (IFFGD) sites:
Chronic Constipation aboutConstipation.org
Acid Reflux Disease (GERD) aboutGERD.org
Motility Disorders aboutGImotility.org
Irritable Bowel Syndrome (IBS) aboutIBS.org
IAMIBS.org
Incontinence or Urgency aboutIncontinence.org
Digestive Disorders in Kids
and Teens
aboutKidsGI.org
Digestive Health Research giResearch.org
Participate in IBS survey


Aurametrix is an early phase company working on better tools for a healthier world.


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Friday, May 1, 2009

Dietary Supplements

back to Aurametrix main page
Mirrored from Aurametrix

Over 50% of people around the globe take supplements, as seen from the polls below. This map (click for interactive version) shows results of a bodybuilding supplements poll:

Snapshots of these open polls (4 open polls, click on the image or a hyperlink to participate or see most recent results), show that most people take vitamins but most of those taking herbal supplements feel so-so about them as they did not observe 'amazing results'.

  • Omega-3’s up the optimism
  • Vitamin D: Sunshine in a bottle
  • Vegan chocolate cheesecake

Created on January 25, 2009 by sfcolleen Ends January 25, 2010

View Results (pick your choice again)


Which healthy supplements do you live by?
Created on May 1, 2009 by John Gamble









Healthy Fats (Olive Oil, Omega-3...)
Green foods (Chlorella...)
Wheat Grass
Juice Blends (Acai, Noni...)
Tea (Yerba Mate, Green...)
Other (Vitamins...)




Show results

US Nutritional Supplements Market is Set to Top $6 Billion by 2011, according to 2006 estimations. In 2007, Americans spent around $20 billion on herbal supplements. By the year 2006, the UK supplement market was valued at $827 million. By 2011, its expected to be worth $868 million. The global nutraceuticals industry sales are forecast to touch $187 billion by 2010, owing to increasing sales in the U.S. and the European Union (EU), as also within the emerging markets like China and India. The estimated prevalence of dietary-supplement use among US adults was 73% in 2002. Nearly four in ten Americans have used herbal supplements such as Echinacea, St. John's Wort, Saw Palmetto and others to try to help a medical problem or as part of their regular diet. Interestingly, unlike the most current results, in 2006 and 2007 most who have tried supplements thought they were are effective, according to CBS News polls, shown below.


Have You Taken Herbal Supplements

(Men)

Yes
31%
No
69%

(Women)

Yes
45%
No
55%


There are also regional differences: Americans who live in the West (44 percent) and East (42 percent) are more likely to have tried supplements than those in the south (36 percent) or Midwest (32 percent).

Do You Think Herbal Supplements Are Generally Helpful?
(All respondents)

Yes
44%
No
33%

Most women and men who have tried supplements think they are generally effective.

Most Americans -55 percent - say they have heard at least something about herbal supplements – and women are more likely than men to have heard a lot. Most men say they've heard little or nothing.

How Much Have You Heard About Herbal Supplements?
(All respondents)

A lot
20%
No
35%
Not much/Some
44%


Younger people under 30 are the most likely to have not heard much about herbal supplements.

For detailed information on how CBS News conducts public opinion surveys, click here.

Interviews were conducted among 993 adults by telephone on January 13, 2007. The error due to sampling for results based on the entire sample could be plus or minus three percentage points.







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Favorite Exercise Polls & Discussions

Most people exercise by walking or running or use gym machines, bodybuilders favor deads & squats, the rest of us try to do a little while on vacation. What about you?
OPEN POLLS:



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